Angular cheilitis most commonly occurs due to prolonged exposure of the corners of the mouth to saliva and its digestive enzymes, resulting in eczematous cheilitis (a form of irritant contact dermatitis)
corners of mouth cracked accutane 15
Angular cheilitis, a condition that causes the corners of the mouth to crack, split, or bleed, can be caused by excess salivation or dehydration. However, it may also be caused by an insufficient intake of iron and B vitamins, particularly riboflavin (10, 11, 12, 13).
Summary People with mouth ulcers or cracks at the corners of the mouth may want to try consuming more foods rich in thiamine, riboflavin, pyridoxine, and iron to alleviate symptoms.
So isotretinoin works by inhibiting sebaceous gland function. Side effects include cheilitis, which is cracking and dryness at corners of the mouth. It can also cause dry skin as well as photosensitivity.
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